RYBP Knowpia

Proteína de unión a RING1 y YY1
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB Lista de códigos PDB 3IXS
Identificadores
Símbolos	RYBP (HGNC: 10480) AAP1; DEDAF; YEAF1
Identificadores; externos	OMIM: 607535 ; HomoloGene: 8159 ; EBI: RYBP; GeneCards: Gen RYBP; UniProt: RYBP;
Locus	Cr. 3 p13
	Referencias: AmiGO / QuickGO
Patrón de expresión de ARNm
	Más información
Ortólogos
Humano	Ratón
23429	56353
Véase HS	Véase MM
Q8N488	Q8CCI5
NM_012234	NM_019743
NP_036366	NP_062717
Cr. 3:; 72.42 – 72.5 Mb	Cr. 6:; 100.23 – 100.29 Mb
[1] ;	[2]
	v; t; e;
	[editar datos en Wikidata]

La proteína de unión a RING1 y YY1 (RYBP) es una proteína codificada en humanos por el gen RYBP.^[1]^[2]

Interacciones

La proteína RYBP ha demostrado ser capaz de interaccionar con:

RING1^[3]^[1]
YY1^[1]
Caspasa 10^[4]
E2F3^[5]
E2F2^[5]
Mdm2^[6]
Gen Abl^[7]
CBX2^[1]

Referencias

↑ ^a ^b ^c ^d García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Agosto de 1999). «RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1». EMBO J (Inglaterra) 18 (12): 3404-18. ISSN 0261-4189. PMC 1171420. PMID 10369680. doi:10.1093/emboj/18.12.3404.
↑ «Entrez Gene: RYBP RING1 and YY1 binding protein».
↑ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct. de 2005). «Towards a proteome-scale map of the human protein-protein interaction network». Nature (England) 437 (7062): 1173-8. PMID 16189514. doi:10.1038/nature04209.
↑ Zheng, L; Schickling O, Peter M E, Lenardo M J (Aug. de 2001). «The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm». J. Biol. Chem. (United States) 276 (34): 31945-52. ISSN 0021-9258. PMID 11395500. doi:10.1074/jbc.M102799200.
↑ ^a ^b Schlisio, Susanne; Halperin Terri, Vidal Miguel, Nevins Joseph R (Nov. de 2002). «Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function». EMBO J. (England) 21 (21): 5775-86. ISSN 0261-4189. PMID 12411495.
↑ Chen, Deng; Zhang Jianbing, Li Mao, Rayburn Elizabeth R, Wang Hui, Zhang Ruiwen (Feb. de 2009). «RYBP stabilizes p53 by modulating MDM2». EMBO Rep. (England) 10 (2): 166-72. PMID 19098711. doi:10.1038/embor.2008.231.
↑ Zhu, J; Shore S K (Dec. de 1996). «c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein». Mol. Cell. Biol. (UNITED STATES) 16 (12): 7054-62. ISSN 0270-7306. PMID 8943360.

Datos: Q18037173

[pmid10369680-1] García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Agosto de 1999). «RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1». EMBO J (Inglaterra) 18 (12): 3404-18. ISSN 0261-4189. PMC 1171420. PMID 10369680. doi:10.1093/emboj/18.12.3404.

[entrez-2] «Entrez Gene: RYBP RING1 and YY1 binding protein».

[pmid16189514-3] Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct. de 2005). «Towards a proteome-scale map of the human protein-protein interaction network». Nature (England) 437 (7062): 1173-8. PMID 16189514. doi:10.1038/nature04209.

[pmid11395500-4] Zheng, L; Schickling O, Peter M E, Lenardo M J (Aug. de 2001). «The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm». J. Biol. Chem. (United States) 276 (34): 31945-52. ISSN 0021-9258. PMID 11395500. doi:10.1074/jbc.M102799200.

[pmid12411495-5] Schlisio, Susanne; Halperin Terri, Vidal Miguel, Nevins Joseph R (Nov. de 2002). «Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function». EMBO J. (England) 21 (21): 5775-86. ISSN 0261-4189. PMID 12411495.

[pmid19098711-6] Chen, Deng; Zhang Jianbing, Li Mao, Rayburn Elizabeth R, Wang Hui, Zhang Ruiwen (Feb. de 2009). «RYBP stabilizes p53 by modulating MDM2». EMBO Rep. (England) 10 (2): 166-72. PMID 19098711. doi:10.1038/embor.2008.231.

[pmid8943360-7] Zhu, J; Shore S K (Dec. de 1996). «c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein». Mol. Cell. Biol. (UNITED STATES) 16 (12): 7054-62. ISSN 0270-7306. PMID 8943360.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

Summary

Interacciones

Referencias