Se reconocen las siguientes:^[1]​

• Mesolestes accentifer (Raffray, 1873)
• Mesolestes affinis (Peringuey, 1896)
• Mesolestes ambiguus Mateu, 1980
• Mesolestes ankaratrae (Mateu, 1975)
• Mesolestes apterus Mateu, 1962
• Mesolestes basilewskyi Mateu, 1962
• Mesolestes bilineatus (Basilewsky, 1949)
• Mesolestes brincki (Mateu, 1965)
• Mesolestes brittoni (Mateu, 1956)
• Mesolestes brunneipes (Mateu, 1980)
• Mesolestes caecus (Antoine, 1941)
• Mesolestes descarpentriesi (Mateu, 1975)
• Mesolestes flavescens (Chaudoir, 1876)
• Mesolestes flavosignatus (Boheman, 1848)
• Mesolestes fraterculus (Chaudoir, 1876)
• Mesolestes fusculus (Peringuey, 1896)
• Mesolestes fuscus Mateu, 1956
• Mesolestes humeralis (Jeannel, 1949)
• Mesolestes innoshimae (Habu, 1974)
• Mesolestes katanganus (Mateu, 1967)
• Mesolestes kilimanus (Alluaud, 1917)
• Mesolestes laevis (Mateu, 1980)
• Mesolestes leleupi (Mateu, 1962)
• Mesolestes machadoi Mateu, 1965
• Mesolestes maculatus Mateu, 1960
• Mesolestes madecassus (Mateu, 1960)
• Mesolestes meridionalis Mateu, 1965
• Mesolestes mirus (Mateu, 1980)
• Mesolestes nigrocephalus Mateu, 1962
• Mesolestes orinodromus (Alluaud, 1907)
• Mesolestes orophilus (Mateu, 1960)
• Mesolestes promontorii (Peringuey, 1899)
• Mesolestes pueli (Antoine, 1923)
• Mesolestes quadriguttatus Mateu, 1979
• Mesolestes relictus (Jeanne, 1985)
• Mesolestes rufus (Mateu, 1967)
• Mesolestes scapularis (Dejean, 1830)
• Mesolestes sellatus (Motschulsky, 1855)
• Mesolestes senegalensis Mateu, 1969
• Mesolestes sermeti (Mateu & Colas, 1954)
• Mesolestes sicardi (Bedel, 1918)
• Mesolestes silvaticus (Mateu, 1967)
• Mesolestes striatus Mateu, 1972
• Mesolestes virgatus (Mateu, 1984)
• Mesolestes vittatus (Mateu, 1979)

•   Wikispecies tiene un artículo sobre Mesolestes.