MEF2D Knowpia

Factor potenciador específico de miocito 2D
	; Estructura tridimensional de la proteína MEF2D.
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB Lista de códigos PDB 1c7u
Identificadores
Símbolos	MEF2D (HGNC: 6997) DKFZp686I1536
Identificadores; externos	OMIM: 600663 ; EBI: MEF2D; GeneCards: Gen MEF2D; UniProt: MEF2D;
Locus	Cr. 1 q22
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
4209
Q14814	n/a
NP_005911	n/a
	v; t; e;
	[editar datos en Wikidata]

La factor potenciador específico de miocito 2D (MEF2D) es una proteína codificada en humanos por el gen mef2D.^[1]^[2]

Interacciones

La proteína MEF2D ha demostrado ser capaz de interaccionar con:

YWHAQ^[3]
MAPK7^[4]
EP300^[5]^[6]
Sp1^[7]
MEF2A^[8]
NFATC2^[9]
CABIN1^[6]^[10]

Véase también

Mef2

Referencias

↑ Breitbart RE, Liang CS, Smoot LB, Laheru DA, Mahdavi V, Nadal-Ginard B (Feb de 1994). «A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage». Development 118 (4): 1095-106. PMID 8269842.
↑ «Entrez Gene: MEF2D MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)».
↑ Choi, S J; Park S Y, Han T H (Jul. de 2001). «14-3-3tau associates with and activates the MEF2D transcription factor during muscle cell differentiation». Nucleic Acids Res. (England) 29 (13): 2836-42. PMID 11433030.
↑ Yang, C C; Ornatsky O I, McDermott J C, Cruz T F, Prody C A (Oct. de 1998). «Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1». Nucleic Acids Res. (ENGLAND) 26 (20): 4771-7. ISSN 0305-1048. PMID 9753748.
↑ Youn, H D; Grozinger C M, Liu J O (Jul. de 2000). «Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4». J. Biol. Chem. (UNITED STATES) 275 (29): 22563-7. ISSN 0021-9258. PMID 10825153. doi:10.1074/jbc.C000304200.
↑ ^a ^b Youn, H D; Liu J O (Jul. de 2000). «Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2». Immunity (UNITED STATES) 13 (1): 85-94. ISSN 1074-7613. PMID 10933397.
↑ Park, So-Youn; Shin Hyun-Mu, Han Tae-Hee (Sep. de 2002). «Synergistic interaction of MEF2D and Sp1 in activation of the CD14 promoter». Mol. Immunol. (England) 39 (1-2): 25-30. ISSN 0161-5890. PMID 12213324.
↑ Ornatsky, O I; McDermott J C (Oct. de 1996). «MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells». J. Biol. Chem. (UNITED STATES) 271 (40): 24927-33. ISSN 0021-9258. PMID 8798771.
↑ Youn, H D; Chatila T A, Liu J O (Aug. de 2000). «Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis». EMBO J. (ENGLAND) 19 (16): 4323-31. ISSN 0261-4189. PMID 10944115. doi:10.1093/emboj/19.16.4323.
↑ Youn, H D; Sun L, Prywes R, Liu J O (Oct. de 1999). «Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2». Science (UNITED STATES) 286 (5440): 790-3. ISSN 0036-8075. PMID 10531067.

Enlaces externos

MeSH: MEF2D+protein,+human (en inglés)

Datos: Q18029011

[pmid8269842-1] Breitbart RE, Liang CS, Smoot LB, Laheru DA, Mahdavi V, Nadal-Ginard B (Feb de 1994). «A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage». Development 118 (4): 1095-106. PMID 8269842.

[entrez-2] «Entrez Gene: MEF2D MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)».

[pmid11433030-3] Choi, S J; Park S Y, Han T H (Jul. de 2001). «14-3-3tau associates with and activates the MEF2D transcription factor during muscle cell differentiation». Nucleic Acids Res. (England) 29 (13): 2836-42. PMID 11433030.

[pmid9753748-4] Yang, C C; Ornatsky O I, McDermott J C, Cruz T F, Prody C A (Oct. de 1998). «Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1». Nucleic Acids Res. (ENGLAND) 26 (20): 4771-7. ISSN 0305-1048. PMID 9753748.

[pmid10825153-5] Youn, H D; Grozinger C M, Liu J O (Jul. de 2000). «Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4». J. Biol. Chem. (UNITED STATES) 275 (29): 22563-7. ISSN 0021-9258. PMID 10825153. doi:10.1074/jbc.C000304200.

[pmid10933397-6] Youn, H D; Liu J O (Jul. de 2000). «Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2». Immunity (UNITED STATES) 13 (1): 85-94. ISSN 1074-7613. PMID 10933397.

[pmid12213324-7] Park, So-Youn; Shin Hyun-Mu, Han Tae-Hee (Sep. de 2002). «Synergistic interaction of MEF2D and Sp1 in activation of the CD14 promoter». Mol. Immunol. (England) 39 (1-2): 25-30. ISSN 0161-5890. PMID 12213324.

[pmid8798771-8] Ornatsky, O I; McDermott J C (Oct. de 1996). «MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells». J. Biol. Chem. (UNITED STATES) 271 (40): 24927-33. ISSN 0021-9258. PMID 8798771.

[pmid10944115-9] Youn, H D; Chatila T A, Liu J O (Aug. de 2000). «Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis». EMBO J. (ENGLAND) 19 (16): 4323-31. ISSN 0261-4189. PMID 10944115. doi:10.1093/emboj/19.16.4323.

[pmid10531067-10] Youn, H D; Sun L, Prywes R, Liu J O (Oct. de 1999). «Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2». Science (UNITED STATES) 286 (5440): 790-3. ISSN 0036-8075. PMID 10531067.

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Summary

Interacciones

Véase también

Referencias

Enlaces externos