Hay unos 109 géneros en la familia Isotomidae:

• Aackia Yosii, 1966
• AcanthomurusWomersley, 1934 ^{c g}
• Aggressopygus Potapov & Babenko, 2014 ^g
• Agrenia Boerner, 1906 ^{i g b}
• Antarcticinella Salmon, 1965 ^g
• Antarctophorus Potapov, 1992 ^{i c g}
• Anurophorus Nicolet, 1842 ^{i c g b}
• Appendisotoma Stach, 1947 ^g
• Araucanocyrtus Massoud & Rapoport, 1968
• Archisotoma Linnaniemi, 1912 ^{i c g}
• Arlea Womersley, 1939
• Axelsonia Boener, 1906 ^{i c g}
• Ballistura Börner, 1906 ^{c g b}
• Biacantha Martynova, 1971 ^g
• Blissia Rusek, 1985 ^{i c g}
• Bonetrura Christiansen and Bellinger, 1980 ^{i c g}
• Burmisotoma Christiansen & Nascimbene, 2006 ^g
• Coloburella Latzel, 1918 ^{i c g}
• Cryptopygus Willem, 1901 ^{i c g}
• Cylindropygus Deharveng, Potapov & Bedos, 2005 ^{i c g}
• Dagamaea Yosii, 1965 ^b
• Degamaea Yosii, 1965 ^{i c g}
• Desoria Agassiz & Nicolet, 1841 ^{c g b}
• Dimorphacanthella Potapov, Bu, Huang, Gao & Luan, 2010 ^g[3]​
• Dimorphotoma Grinbergs, 1975 ^g
• Ephemerotoma ^g
• Folsomia Willem, 1902 ^{i c g b}
• Folsomides Stach, 1922 ^{i c g}
• Folsomina Denis, 1931 ^{i c g}
• Folsomotoma ^{c g}
• Gnathisotoma Cassagnau, 1957 ^g
• Gnathofolsomia Deharveng & Christian, 1984 ^g
• Gressittacantha Wise, 1967 ^{i c g}
• Guthriella Börner, 1906 ^{g b}
• Halisotoma ^{c g}
• Haploisotoma Izarra, 1965 ^{i c g}
• Hemisotoma Bagnall, 1949 ^{i c g}
• Heteroisotoma Stach, 1947 ^g
• Hydroisotoma Stach, 1947 ^{g b}
• Isotoma Bourlet, 1839 ^{i c g b}
• IsotomediaSalmon, 1944 ^{c g}
• Isotomiella Bagnall, 1939 ^{i c g b}
• Isotomina ^g
• Isotomodella Martynova, 1968 ^{i c g}
• Isotomodes Axelson, 1907 ^{i c g}
• Isotomurus Boerner, 1903 ^{i c g b}
• Isotopenola Potapov, Babenko, Fjellberg & Greenslade, 2009 ^g
• Jesenikia Rusek, 1997 ^{i c g}
• Jestella Najt, 1978
• Kaylathalia Stevens & D'Haese, 2016 ^g
• Marisotoma Fjellberg, 1997 ^g
• Martynovella Deharveng, 1978 ^g
• Metisotoma Maynard, 1951 ^{i c g b}
• Micranurophorus Bernard, 1977 ^{i c g}
• Micrisotoma Bellinger, 1952 ^{i c g}
• Millsia Womersley, 1942
• Mucracanthus Stebaeva, 1976
• Mucronia Fjellberg ^g
• Mucrosomia Bagnall, 1949 ^{i c g}
• Mucrotoma Rapoport & Rubio, 1963 ^{i c g}
• Myopia Chrisiansen & Bellinger, 1980 ^g
• Narynia Martynova, 1967 ^g
• Neocryptopygus Salmon, 1965 ^{i c g}
• Neophorella Womersley, 1934
• Octodontophora Chelnokov, 1990
• Pachyotoma Bagnall, 1949 ^g
• Papillomurus ^{c g}
• Paracerura Deharveng & de Olivei, 1994 ^g
• Parafolsomia Salmon, 1949 ^g
• Parisotoma Bagnall, 1940 ^{c g b}
• Pectenisotoma Gruia, 1983 ^{i c g}
• Pentacanthella Deharveng, 1979
• ProceruraSalmon, 1941 ^{c g}
• Proctostephanus Börner, 1902 ^{i c g}
• Proisotoma Börner, 1901 ^{i c g b}
• Proisotomurus ^{c g}
• Propachyotoma Christiansen & Nascimbene, 2006 ^g
• Protodesoria Christiansen & Nascimbene, 2006 ^g
• Protoisotoma Christiansen & Pike, 2002 ^g
• Psammisotoma Greenslade & Deharveng, 1986 ^g
• Pseudanurophorus Stach, 1922 ^{i c g}
• Pseudisotoma Handschin, 1924 ^{g b}
• Pseudofolsomia Martynova, 1967 ^g
• Pteronychella Börner, 1909
• Rhodanella Salmon, 1945 ^{i c g}
• Sahacanthella Potapov & Stebaeva, 1994
• Salmonia Baijal, 1958
• Scutisotoma Bagnall, 1949 ^{g b}
• Secotomodes Potapov, 1988
• Semicerura Maynard, 1951 ^{i c g}
• Sericeotoma Potapov, 1991 ^g
• Setocerura Salmon, 1949 ^{c g}
• Sibiracanthella Potapov & Stebaeva, 1995 ^{i c g}
• Skadisotoma ^g
• SpinoceruraSalmon, 1941 ^{c g}
• Stachanorema Wray, 1957 ^{i c g}
• Strenzketoma Potapov & al., 2006 ^g
• Subisotoma ^g
• Tetracanthella Schött, 1891 ^{i c g}
• Tiancanthella Rusek, 1979
• Tibiolatra Salmon, 1941 ^{c g}
• Tomocerura Wahlgren, 1901 ^{c g}
• Tuvia Grinbergs, 1962 ^{i c g}
• Uzelia Absolon, 1901 ^{i c g}
• Vertagopus Börner, 1906 ^{g b}
• Villusisotoma Christiansen & Nascimbene, 2006 ^g
• Weberacantha Christiansen, 1951 ^{i c g}
• Womersleyella Salmon, 1944 ^{i c g}
• Yosiiella Hüther, 1967 ^{i c g}

Fuentes de información: i = ITIS,^[4]​ c = Catalogue of Life,^[5]​ g = GBIF,^[6]​ b = Bugguide.net^[7]​