ETS2 Knowpia

V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
	; Estructura tridimensional de la proteína ETS2.
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB Lista de códigos PDB 1k78
Identificadores
Símbolo	ETS2 (HGNC: 3489)
Identificadores; externos	OMIM: 164740 ; EBI: ETS2; GeneCards: Gen ETS2; UniProt: ETS2;
Locus	Cr. 21 q22.2
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
2114
P15036	n/a
NP_005230	n/a
	v; t; e;
	[editar datos en Wikidata]

La proteína C-ets-2 (V-ets erythroblastosis virus E26 oncogene homolog 2 (avian) o ETS2) es una proteína codificada en humanos por el gen ets2.^[1]^[2] La proteína codificada por este gen pertenece a la familia de los factores de transcripción ETS.^[1]

Interacciones

La proteína ETS2 ha demostrado ser capaz de interaccionar con:

ZMYND11^[3]
ERG^[4]
Cdk10^[5]
c-Jun^[4]

Referencias

↑ ^a ^b Dwyer J, Li H, Xu D, Liu JP (octubre de 2007). «Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family». Ann. N. Y. Acad. Sci. 1114: 36-47. PMID 17986575. doi:10.1196/annals.1396.022.
↑ «Entrez Gene: ETS2 V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)».
↑ Wei, Guo; Schaffner Alicia Erbe, Baker Kimberly M, Mansky Kim C, Ostrowski Michael C. «Ets-2 interacts with co-repressor BS69 to repress target gene expression». Anticancer Res. (Greece) 23 (3A): 2173-8. ISSN 0250-7005. PMID 12894593.
↑ ^a ^b Basuyaux, J P; Ferreira E, Stéhelin D, Butticè G (Oct. de 1997). «The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner». J. Biol. Chem. (UNITED STATES) 272 (42): 26188-95. ISSN 0021-9258. PMID 9334186.
↑ Kasten, M; Giordano A (Apr. de 2001). «Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity». Oncogene (England) 20 (15): 1832-8. ISSN 0950-9232. PMID 11313931. doi:10.1038/sj.onc.1204295.

Enlaces externos

Drosophila pointed - La mosca interactiva

Datos: Q17917643

[pmid17986575-1] Dwyer J, Li H, Xu D, Liu JP (octubre de 2007). «Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family». Ann. N. Y. Acad. Sci. 1114: 36-47. PMID 17986575. doi:10.1196/annals.1396.022.

[2] «Entrez Gene: ETS2 V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)».

[pmid12894593-3] Wei, Guo; Schaffner Alicia Erbe, Baker Kimberly M, Mansky Kim C, Ostrowski Michael C. «Ets-2 interacts with co-repressor BS69 to repress target gene expression». Anticancer Res. (Greece) 23 (3A): 2173-8. ISSN 0250-7005. PMID 12894593.

[pmid9334186-4] Basuyaux, J P; Ferreira E, Stéhelin D, Butticè G (Oct. de 1997). «The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner». J. Biol. Chem. (UNITED STATES) 272 (42): 26188-95. ISSN 0021-9258. PMID 9334186.

[pmid11313931-5] Kasten, M; Giordano A (Apr. de 2001). «Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity». Oncogene (England) 20 (15): 1832-8. ISSN 0950-9232. PMID 11313931. doi:10.1038/sj.onc.1204295.

[1]

[2]

[3]

[4]

[5]

Summary

Interacciones

Referencias

Enlaces externos